Nutrition as therapy - Background

Dr Ashraf Virmani

Dietary therapy provides a powerful tool for correcting disharmonies and micro deficiencies which can affect the fundamental metabolic and physiological systems of the body. Proper nutrition can help in conditions ranging from allergy to diabetes and cancer. 

You are what you eat - is not just a saying by the old folk but a truth that has been known since ancient times. After the zeal of the western scientists in last 50 or 60 years following their success in replication (chemical synthesis) of products like digitalis, aspirin and antibiotics (all natural herbal products) and the growth of the chemically-based pharmaceutical industry, it has been the public that has been in the forefront to the return to 'natural' treatments based on prevention rather than cure. It is rather strange that the academic and  medical profession remained largely resistant and close minded to this evolution instead of leading it. It was the researchers from the East together with various enlightened individuals in the west (considered hippies or worse) who in the last 30 to 40 year persevered with alternative medicines and now the 'status quo' have seen the potential they have jumped aboard this new field, now also referred to as 'Nutritional Pharmacology'.

The components of the food are broken down and absorbed into the blood stream and form there they are taken to various tissues and organs. These substances affect the metabolic and even the physical status of these organs and tissues. The effects are even more profound than previously imagined since the actual genetic response at the cellular level is changed.

The state of nutrition and therefore function of the tissues and organs is affected and this can affect not only the individuals overall health and risk of contracting disease or malfunction, but also the health of the offspring. For example, in a malnourished mother the placenta may not be adequately developed and this will affect the fetus, and increases its risk in later life of contracting disease. This domino effect could already depend on the grandmothers nutritional state or her mother before that !

Thus a great part of one's health destiny is predetermined in the fetal stage and younger age but some of this destiny can be modified in a positive manner even in later life by compensatory nutritional diets.

In  diabetes disease pathology, insulin resistance appears to be a common feature and a possible contributing factor to several frequent health problems, including type 2 diabetes mellitus, polycystic ovary disease, dyslipidemia, hypertension, cardiovascular disease, sleep apnea, certain hormone-sensitive cancers, and obesity. Modifiable factors thought to contribute to insulin resistance include diet, exercise, smoking, and stress. Lifestyle intervention to address these factors appears to be a critical component of any therapeutic approach. The role of nutritional and botanical substances in the management of insulin resistance requires further elaboration; however, available information suggests some substances are capable of positively influencing insulin resistance. 

Minerals such as magnesium, calcium, potassium, zinc, chromium, and vanadium appear to have associations with insulin resistance or its management. Amino acids, including L-carnitine, taurine, and L-arginine, might also play a role in the reversal of insulin resistance. Other nutrients, including glutathione, coenzyme Q10, and lipoic acid, also appear to have therapeutic potential.

Polyunsaturated fatty acids of the omega 3 series, such as eicosopentanoic acid (EPA) may also be useful in diabetes and other autoimmune type diseases due to their immunosuppresant and anti-inflammatory properties.

Research on herbal medicines for the treatment of insulin resistance is limited; however, silymarin produced positive results in diabetic patients with alcoholic cirrhosis, and Inula racemosa potentiated insulin sensitivity in an animal model.

Look up further information on the various components of nutrition: Information on Nutrition

Apples can keep the doctor away (BBC article)

References

Kelly GS Insulin resistance: lifestyle and nutritional interventions. Altern Med Rev 2000 Apr;5(2):109-32

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